Years before her fame, Kristine started out as Baron Geisler‘s loveteam partner in Nagbibinata. Later on, she was cast in Sa Sandaling Kailangan Mo Ako, a weekly drama series together with Marvin Agustin. She garnered critical acclaim for her performance in this series as she was portraying a role almost more than five years older than her real age.
She was linked to Diether Ocampo until it became a real-life romance on the set of Sana’y Wala ng Wakas. Later, the two got married. Also, their TV series together with her then real-life boyfriend Til Death Do Us Part was a major flop. In 2005, she was given the role of Luisa in the much-loved classic Gulong ng Palad together with new partner TJ Trinidad where she returned to the limelight after taking a break from acting in a TV series.
Hermosa is a member of ABS-CBN’s elite circle of homegrown talents properly named Star Magic. She is also voted no. 2 Most Beautiful Filipina of 2006.